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Updated: May 30, 2026
Determination of the Excitation and Coupling Rates Between Light Emitters and Surface Plasmon Polaritons
Published on: July 21, 2018
Wavelength-Selective Light-Induced Release from Plasmon Resonant Liposomes
Sarah J Leung1, Xenia M Kachur, Michael C Bobnick
1Department of Biomedical Engineering, University of Arizona, 1657 E. Helen Street, Tucson, AZ 85721, USA.
Researchers developed biodegradable gold nanocapsules for targeted drug delivery. These nanocapsules release contents selectively using specific light wavelengths, offering a safe and efficient method for various applications.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Thermosensitive liposomes offer controlled release capabilities.
- Plasmon resonance in nanoparticles can be tuned for specific light interactions.
- Gold nanoparticles are biocompatible and have unique optical properties.
Purpose of the Study:
- To create biodegradable, spectrally tunable plasmon resonant nanocapsules.
- To demonstrate selective release of encapsulated contents using light.
- To explore applications in drug delivery, microfluidics, and sensors.
Main Methods:
- Deposition of gold onto thermosensitive liposomes (100 nm diameter).
- Characterization of plasmon resonance bands (760 nm and 1210 nm).
- Illumination with multiple, low-intensity laser pulses for selective release.
Main Results:
- Successfully synthesized gold-coated nanocapsules with tunable plasmon resonance.
- Achieved spectrally selective release of encapsulated contents at specific wavelengths.
- Demonstrated a rapid (under four minutes) and localized release mechanism.
Conclusions:
- The developed nanocapsules provide a biologically safe drug delivery mechanism.
- The technology is suitable for microfluidic and sensor applications.
- Tunable plasmon resonance enables precise control over content release.
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