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Updated: May 30, 2026

Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
Gastric carcinoid in a patient infected with Helicobacter pylori: a new entity?
Pantelis Antonodimitrakis1, Apostolos Tsolakis, Staffan Welin
1Department of Medical Sciences, Division of Endocrine Oncology, University Hospital of Uppsala, Uppsala 75900, Sweden. pantelis.antonodimitrakis@akademiska.se
Abstract:
There are four types of gastric carcinoid tumors, classified according to their histology and malignant potential. Only a few cases of carcinoid tumors in patients infected with Helicobacter pylori (H. pylori) have been reported so far. We report a patient infected with H. pylori presenting with a small solitary gastric carcinoid tumor with very low proliferative rate and normal gastrin levels. The tumor was endoscopically removed and the patient received an eradication therapy against H. pylori. No signs of metastatic disease have been found so far during more than 3 year of follow-up. Infection with H. pylori may cause chronic gastritis with normal or elevated gastrin levels, leading to the development of gastric carcinoids by mechanisms unrelated to gastrin. Enterochromaffin-like cell tumors related to a chronic H. pylori infection may be considered as a distinct type of gastric carcinoid tumors.
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