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Related Concept Videos

Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Entropy Changes Accompanying Specific Processes01:21

Entropy Changes Accompanying Specific Processes

Entropy, a measure of disorder in a system, changes during phase transitions like freezing or boiling. At the transition temperature Ttrs, where two phases are in equilibrium, the phase transition is a reversible process. The entropy change can be calculated from a substance's enthalpy of transition using the equation ΔStrs = ΔtrsH /Ttrs.When a perfect gas expands isothermally from one volume to another, entropy increases logarithmically with volume. Conversely, isothermal compression results...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Intracellular Movement of Viruses and Bacteria01:10

Intracellular Movement of Viruses and Bacteria

Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a virus that...
Diversity of Protists IV01:27

Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...

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Trajectory Data Analyses for Pedestrian Space-time Activity Study
16:14

Trajectory Data Analyses for Pedestrian Space-time Activity Study

Published on: February 25, 2013

Phase transitions in contagion processes mediated by recurrent mobility patterns.

Duygu Balcan1, Alessandro Vespignani

  • 1Center for Complex Networks and Systems Research (CNetS), School of Informatics and Computing, Indiana University, Bloomington, IN 47408, USA.

Nature Physics
|July 30, 2011
PubMed
Summary
This summary is machine-generated.

Human mobility patterns influence contagion spread. A new framework reveals a critical threshold for contagion, offering insights into controlling disease or information diffusion by managing movement.

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07:40

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Published on: October 29, 2016

Area of Science:

  • Complex systems
  • Epidemiology
  • Network science

Background:

  • Human mobility and activity patterns are key drivers of contagion, affecting disease spread, rumor diffusion, and consensus formation.
  • Traditional models often use random diffusive dynamics, which inadequately capture the recurrent flows and location-specific nature of human movement.

Purpose of the Study:

  • To develop a theoretical framework for analyzing contagion within a network of locations considering individuals' geographic origins.
  • To identify and characterize a phase transition in contagion dynamics based on mobility patterns.

Main Methods:

  • Development of a theoretical framework to model contagion in a network of locations with origin recall.
  • Analysis of stochastic contagion processes and their phase transition behavior.
  • Validation using diffusion processes on real human commuting data.

Main Results:

  • Identification of a phase transition between high and low contagion regimes.
  • Discovery that continuous models fail to capture this transition due to stochasticity.
  • Definition of an invasion threshold dependent on mobility parameters.

Conclusions:

  • The study provides a novel framework for understanding contagion dynamics influenced by human mobility.
  • The identified invasion threshold offers guidance for controlling contagion spread by strategically constraining mobility.
  • The findings highlight the importance of incorporating realistic mobility patterns into contagion models.