Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution

Jayakumar Rajadas1, Corey W Liu, Paul Novick

  • 1Biomaterials and Advanced Drug Delivery Laboratory, Stanford University, Stanford, California, United States of America.

Plos One
|July 30, 2011
PubMed
Summary

Researchers engineered a mutant beta amyloid peptide (Aβ(42)) to create stable oligomers, offering insights into Alzheimer

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