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Prevalence and predictors of vitamin D insufficiency in children: a Great Britain population based study
Michael Absoud1, Carole Cummins, Ming J Lim
1School of Health and Population Sciences, University of Birmingham, Birmingham, United Kingdom. michaelabsoud@childdemyelination.org.uk
Insights
Vitamin D insufficiency (VDI) affects 35% of children in Great Britain, particularly adolescents and non-white children. Modifiable factors like low outdoor activity and overweight increase VDI risk.
Area of Science:
- Pediatric Nutrition
- Public Health
- Endocrinology
Background:
- Vitamin D insufficiency (VDI) is a growing concern in pediatric populations globally.
- Identifying prevalence and risk factors in specific demographics is crucial for targeted interventions.
Purpose of the Study:
- To determine the prevalence of vitamin D insufficiency (VDI) in children across Great Britain.
- To identify key predictors associated with VDI in this pediatric cohort.
Main Methods:
- A nationally representative cross-sectional study surveyed 1102 children aged 4-18 years.
- Data collected included demographics, lifestyle factors, and serum vitamin D levels.
- VDI was defined as serum levels below 50 nmol/L.
Main Results:
- 35% of children exhibited vitamin D insufficiency (VDI), with levels decreasing with age.
- Significant risk factors for VDI included: adolescence, non-white ethnicity, lower latitude living, winter blood draws, lower income, overweight status, reduced outdoor activity, and increased screen time.
- Dietary intake and gender did not significantly impact vitamin D status.
Conclusions:
- Adolescents and non-white children represent high-risk groups for VDI and should be targeted in prevention strategies.
- Modifiable risk factors such as physical activity, screen time, and weight management may help mitigate VDI.
- There is a need for increased awareness and clearer guidelines regarding vitamin D supplementation in older children.
Objectives:
To evaluate the prevalence and predictors of vitamin D insufficiency (VDI) in children in Great Britain.
Design:
A nationally representative cross-sectional study survey of children (1102) aged 4-18 years (999 white, 570 male) living in private households (January 1997-1998). Interventions provided information about dietary habits, physical activity, socio-demographics, and blood sample. Outcome measures were vitamin D insufficiency (<50 nmol/L).
Results:
Vitamin D levels (mean = 62.1 nmol/L, 95%CI 60.4-63.7) were insufficient in 35%, and decreased with age in both sexes (p<0.001). Young People living between 53-59 degrees latitude had lower levels (compared with 50-53 degrees, p = 0.045). Dietary intake and gender had no effect on vitamin D status. A logistic regression model showed increased risk of VDI in the following: adolescents (14-18 years old), odds ratio (OR) = 3.6 (95%CI 1.8-7.2) compared with younger children (4-8 years); non white children (OR = 37 [95%CI 15-90]); blood levels taken December-May (OR = 6.5 [95%CI 4.3-10.1]); on income support (OR = 2.2 [95%CI 1.3-3.9]); not taking vitamin D supplementation (OR = 3.7 [95%CI 1.4-9.8]); being overweight (OR 1.6 [95%CI 1.0-2.5]); <1/2 hour outdoor exercise/day/week (OR = 1.5 [95%CI 1.0-2.3]); watched >2.5 hours of TV/day/week (OR = 1.6[95%CI 1.0-2.4]).
Conclusion:
We confirm a previously under-recognised risk of VDI in adolescents. The marked higher risk for VDI in non-white children suggests they should be targeted in any preventative strategies. The association of higher risk of VDI among children who exercised less outdoors, watched more TV and were overweight highlights potentially modifiable risk factors. Clearer guidelines and an increased awareness especially in adolescents are needed, as there are no recommendations for vitamin D supplementation in older children.
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