Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Next-generation integrated microfluidic circuits.

Bobak Mosadegh1, Tommaso Bersano-Begey, Joong Yull Park

  • 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, 48109, USA.

Lab on a Chip
|July 30, 2011
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanoadaptive root growth in <i>Medicago sativa</i> under controlled microhydrodynamic environments.

Lab on a chip·2026
Same author

A Swivel Microwell Platform for Rotational Assembly and Co-culture of Multiple Spheroids.

Biofabrication·2026
Same author

Acoustic-based Stenosis Detection for Dialysis Patients using Explainable Machine Learning.

Research square·2026
Same author

Prognostic Modeling of Tricuspid Valve Regurgitation Outcomes Using Machine Learning-Based Survival Analysis.

Journal of clinical medicine·2026
Same author

Yeast-powered microfluidic pump based on a four-parameter fermentation model.

Microsystems & nanoengineering·2026
Same author

HYPER-Net: Physics-Conditioned Self-Supervised Reconstruction for Fourier Light-Field Microscopy.

bioRxiv : the preprint server for biology·2026

New microfluidic devices use novel valve networks to simplify control, reducing the need for numerous external connections. These innovations enable complex operations on microfluidic chips with fewer control lines.

Area of Science:

  • Microfluidics
  • Mechanical Engineering
  • Biotechnology

Background:

  • Conventional microfluidic systems often require numerous external control lines, creating complex interconnects.
  • The number of control lines typically increases with the number of independently operated valves, posing a design challenge.

Purpose of the Study:

  • To review recent advancements in microfluidic devices that minimize or eliminate external interconnections for flow control.
  • To highlight strategies for simplifying microfluidic chip control and enabling more complex functionalities.

Main Methods:

  • Overview of devices utilizing networks of elastomeric valves for flow control.
  • Discussion of serial encoding of information for valve instruction.
  • Exploration of microfluidic circuit-embedded encoding to eliminate control lines.

More Related Videos

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
07:51

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Development of New Therapeutic Applications Using Microfluidics
08:56

Development of New Therapeutic Applications Using Microfluidics

Published on: October 1, 2007

Related Experiment Videos

Last Updated: May 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
07:51

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Development of New Therapeutic Applications Using Microfluidics
08:56

Development of New Therapeutic Applications Using Microfluidics

Published on: October 1, 2007

Main Results:

  • Devices described circumvent the "tyranny of microfluidic interconnects" by serial or embedded information encoding.
  • These approaches allow instruction of numerous valves with a limited number of control lines or no external lines at all.
  • Parallel instruction chips, though historical, remain common but are limited in complexity.

Conclusions:

  • Next-generation integrated microfluidic circuits will benefit from advanced interconnect flow control approaches.
  • Serial and embedded encoding strategies are crucial for enabling complex chip-to-chip communication and real-time feedback control.
  • These innovations pave the way for more sophisticated and user-friendly microfluidic systems.