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Related Concept Videos

Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Anatomy of the Ear01:16

Anatomy of the Ear

Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.

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Related Experiment Video

Updated: May 30, 2026

Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
09:23

Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

Published on: May 24, 2018

Spine formation and maturation in the developing rat auditory cortex.

Scott J Schachtele1, Joe Losh, Michael E Dailey

  • 1Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242-1109, USA.

The Journal of Comparative Neurology
|July 30, 2011
PubMed
Summary
This summary is machine-generated.

Auditory cortex development involves rapid formation and maturation of dendritic spines and filopodia. This structural development correlates with the refinement of the tonotopic map in young rats.

More Related Videos

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
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Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve
11:27

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve

Published on: March 18, 2013

Related Experiment Videos

Last Updated: May 30, 2026

Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
09:23

Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

Published on: May 24, 2018

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
09:29

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain

Published on: October 11, 2017

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve
11:27

Selective Tracing of Auditory Fibers in the Avian Embryonic Vestibulocochlear Nerve

Published on: March 18, 2013

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Auditory System Research

Background:

  • The rat auditory cortex tonotopic map refines postnatally, but underlying structural changes are unclear.
  • Understanding synaptogenesis is key to auditory cortex development.

Purpose of the Study:

  • To investigate the structural basis of auditory cortex tonotopic map maturation.
  • To quantify synaptogenesis and dendritic protrusion development in developing rat auditory cortex.

Main Methods:

  • Utilized fluorescent dye ballistic labeling (DiOlistics) and immunohistochemistry.
  • Quantified dendritic protrusions (filopodia and spines) on neurons in layers 2/3, 4, and 5.
  • Developed a novel method combining DiOlistics and bassoon labeling to differentiate protrusion types.

Main Results:

  • Dendritic protrusion formation occurs in three phases: slow addition (P4-P9), rapid addition (P9-P19), and maturation (>P21).
  • A rapid increase in the spine-to-filopodium ratio (P9-P16) indicates significant spine maturation.
  • Protrusion length decreased between P9-P16, supporting spine maturation.

Conclusions:

  • Dendritic protrusion formation and spine maturation are rapid during auditory cortical tonotopic map refinement (P11-P14).
  • These structural changes provide a correlate for the physiological maturation of the auditory cortex.