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Related Experiment Video

Updated: May 30, 2026

Efficacy of Fu's Subcutaneous Needling on Sciatic Nerve Pain: Behavioral and Electrophysiological Changes in a Chronic Constriction Injury Rat Model
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[Automated intermittent bolus infusion for continuous sciatic nerve block: a case report].

Atsushi Hashimoto1, Hiroshi Ito, Yuko Sato

  • 1Department of Anesthesiology, Aichi Medical University, Aichi 480-1195.

Masui. the Japanese Journal of Anesthesiology
|August 2, 2011
PubMed
Summary

Automated intermittent bolus infusion for sciatic nerve blocks effectively managed severe pain in critical limb ischemia (CLI) patients unresponsive to continuous infusion. This technique offers improved analgesia for refractory CLI pain.

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Area of Science:

  • Anesthesiology
  • Pain Management
  • Vascular Surgery

Background:

  • Critical limb ischemia (CLI) often causes severe, refractory pain.
  • Systemic analgesics and conventional nerve blocks may be insufficient for CLI pain management.

Observation:

  • Two cases of CLI with severe lower extremity pain are presented.
  • Case 1: Ultrasound-guided popliteal nerve catheter with automated intermittent bolus infusion of ropivacaine provided effective analgesia.
  • Case 2: Automated intermittent bolus infusion via popliteal sciatic nerve block provided inadequate pain relief despite previous interventions.

Findings:

  • Automated intermittent bolus infusion via peripheral nerve catheter demonstrated variable efficacy in managing severe CLI pain.
  • Patient-controlled analgesia with intermittent bolus infusions may offer superior pain control compared to continuous infusions in select CLI patients.

Implications:

  • Automated intermittent bolus infusion represents a potential alternative for managing refractory ischemic pain in CLI.
  • Further research is warranted to optimize patient selection and protocols for this analgesic technique in CLI.
  • This approach may improve quality of life for patients suffering from severe ischemic limb pain.