A highly selective, fluorescent chemosensor for bioimaging of Fe³⁺
Lizhu Zhang1, Jingyun Wang, Jiangli Fan
1State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Rd., Hi-tech Zone, Dalian 116024, PR China.
Bioorganic & Medicinal Chemistry Letters
|August 2, 2011
Abstract:
A fluorescent sensor for Fe(3+) has been synthesized based on rhodamine-lactam, which shows excitation (531 nm) and emission (557 nm) wavelength, displays an excellent selectivity for Fe(3+) and can be used for imaging Fe(3+) in living cells. The pK(a) of the sensor is as low as of 3.2. It can be used in the range of pH 5-9.
