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Low-intensity IVF: real progress?

Norbert Gleicher1, Andrea Weghofer, David H Barad

  • 1Center for Human Reproduction, New York and Foundation for Reproductive Medicine, New York, NY, USA. ngleicher@thechr.com

Reproductive Biomedicine Online
|August 2, 2011
PubMed

A recent publication in this journal strongly advocated low-intensity IVF (LI-IVF) after presenting the authors' experience with minimal ovarian stimulation (mini-IVF). The data presented failed to support their conclusions. Therefore, presented here is a critique of their manuscript and of uncontrolled clinical use of LI-IVF, in general. In the absence of properly controlled studies, all forms of LI-IVF should be considered experimental and be offered only in well-controlled research settings and with appropriate informed consent.

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