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Updated: May 30, 2026
11:26
Sequencing of mRNA from Whole Blood using Nanopore Sequencing
Published on: June 3, 2019
High throughput DNA sequencing: The new sequencing revolution.
Michel Delseny1, Bin Han, Yue Ie Hsing
1Laboratoire Génome et Développement des Plantes, UMR5096 CNRS-IRD-UP, University of Perpignan, 58 av. Paul Alduy, 66860 Perpignan, France. delseny@univ-perp.fr
Summary
Technological advancements in DNA sequencing are revolutionizing plant science, enabling new research and breeding strategies. This review covers sequencing methods, plant genome achievements, and their impact on biodiversity and agriculture.
Area of Science:
- Plant Science
- Genomics
- Bio-medical Research
Background:
- Rapid technological advancements in DNA sequencing are transforming biological research.
- Plant science has significantly benefited from these breakthroughs, leading to increased availability of plant genomes.
Purpose of the Study:
- To review the principles of new DNA sequencing technologies.
- To summarize the current state and recent achievements in plant genome sequencing.
- To discuss the impact of genome sequencing on plant biodiversity, gene expression, and epigenetics.
Main Methods:
- Description of novel sequencing methodologies.
- Review of published plant genome sequencing projects and findings.
- Analysis of discoveries in plant genome structure, evolution, and regulation.
Main Results:
- Numerous plant genomes have been sequenced, opening new avenues for research.
- Significant progress has been made in understanding plant genome structure and evolution.
- Genome sequencing has influenced plant breeding and biodiversity conservation efforts.
Conclusions:
- The field of plant genomics is entering a new era driven by advanced sequencing technologies.
- Genome sequencing provides crucial insights for improving plant breeding and protecting biodiversity.
- Future trends, challenges, and perspectives in plant genome sequencing are discussed.
Related Concept Videos
03:00Next-generation Sequencing
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.
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01:05Maxam-Gilbert Sequencing
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03:21RNA-seq
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Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...
02:02Genomics
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...