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Related Concept Videos

Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Sources of Food Contamination01:29

Sources of Food Contamination

Contamination of food by microbial agents and natural toxins poses significant risks to public health. These hazards can be introduced at various points across the food supply chain, ranging from environmental sources to processing and storage stages. Understanding these contamination pathways is critical for developing strategies to ensure food safety.Seafood is particularly vulnerable to contamination through both environmental exposure and microbial colonization. Toxins from harmful algal...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

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Related Experiment Video

Updated: May 30, 2026

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages
09:39

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages

Published on: May 30, 2013

Cholera: a great global concern.

Shyamapada Mandal1, Manisha Deb Mandal, Nishith Kumar Pal

  • 1Department of Zoology, Gurudas College, Narkeldanga, Kolkata-700 054, India. samtropmed@gmail.com

Asian Pacific Journal of Tropical Medicine
|August 2, 2011
PubMed
Summary
This summary is machine-generated.

Cholera, a severe diarrheal disease caused by Vibrio cholerae, poses a global threat. Safe oral vaccines offer a promising intervention to control multidrug-resistant infections and curb cholera

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Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

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Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview
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Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview

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Last Updated: May 30, 2026

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages
09:39

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages

Published on: May 30, 2013

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview
06:44

Vibrio cholerae: Model Organism to Study Bacterial Pathogenesis - Interview

Published on: May 28, 2007

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Cholera is a life-threatening diarrheal disease caused by toxigenic Vibrio cholerae (V. cholerae), with epidemic and pandemic potential.
  • V. cholerae produces cholera toxin, responsible for the disease's lethal symptoms. Multidrug-resistant strains are emerging globally.
  • Cholera is becoming endemic in many regions, indicating challenges in control measure implementation.

Purpose of the Study:

  • To review the facts and phenomena related to cholera.
  • To highlight cholera as a significant threat, particularly to developing countries.
  • To discuss current challenges and potential interventions for cholera control.

Main Methods:

  • This is a review article, synthesizing existing knowledge on cholera.
  • Information is gathered from various sources to describe the disease's epidemiology, pathogenesis, and control.

Main Results:

  • Fluid and electrolyte replacement is the primary treatment; antibiotics are used for severe cases.
  • Antibiotic resistance in V. cholerae is a growing problem, complicating treatment and leading to outbreaks.
  • Current oral cholera vaccines are safe and effective in reducing infections and could help control antibiotic resistance.

Conclusions:

  • Improved public health interventions (water, sanitation, healthcare) are crucial for cholera control.
  • Development of safe and effective vaccines is essential.
  • Cholera remains a grave global concern, necessitating continued efforts in prevention and control.