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Related Concept Videos

Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Updated: May 30, 2026

Gold Nanoparticle Synthesis
13:42

Gold Nanoparticle Synthesis

Published on: July 10, 2021

Dense aqueous colloidal gold nanoparticles prepared from highly concentrated precursor solution.

Tetsuro Soejima1, Seisaku Oshiro, Yasuji Nakatsuji

  • 1Department of Applied Chemistry, Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan. soejima@apch.kindai.ac.jp

Journal of Colloid and Interface Science
|August 2, 2011
PubMed
Summary

Researchers developed a rapid method to create stable gold and silver nanoparticle powders using casein proteins. These powders easily re-disperse into dense colloidal solutions, offering a scalable approach for nanoparticle synthesis.

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Biochemistry

Background:

  • Gold nanoparticles (AuNPs) are crucial in various applications.
  • Efficient synthesis of stable, concentrated nanoparticle solutions remains a challenge.

Purpose of the Study:

  • To develop a rapid, one-pot synthesis for concentrated gold and silver nanoparticle powders.
  • To utilize casein proteins for stabilizing metal nanoparticles.
  • To achieve high re-dispersion of nanoparticle powders into stable colloidal solutions.

Main Methods:

  • Fabrication of gold nanoparticles via reduction of high-concentration Au(III) ions with casein.
  • Conversion of nanoparticles to powders through washing and vacuum drying.
  • Characterization using UV-vis spectroscopy, dynamic light scattering (DLS), and Fourier transform infrared (FT-IR) spectroscopy.
  • Development of casein-protected gold and silver nanoparticle synthesis using 3-amino-1-propanol.

Main Results:

  • Stable gold nanoparticle powders were produced without aggregation, re-dispersing into colloidal solutions.
  • Dynamic formation and disintegration of casein-Au(III) ion-nanoparticle assemblies were observed.
  • Casein protein conformational changes were confirmed due to interactions with Au(III) ions and gold nanoparticles.
  • Rapid synthesis yielded casein-protected gold and silver nanoparticle powders (below 10 nm) with high re-dispersion capabilities.
  • Dense colloidal gold (40 g L(-1)) and silver (22 g L(-1)) solutions were obtained.

Conclusions:

  • Casein proteins effectively stabilize gold and silver nanoparticles, enabling powder formation and re-dispersion.
  • A scalable, one-pot method for producing concentrated metal nanoparticle solutions was successfully established.
  • The developed method offers a promising route for the industrial application of metal nanoparticles.