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Updated: May 30, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Application of Hemostatic Devices in Laparoscopic Hepatectomy

Published on: April 19, 2022

Postoperative bleeding in a patient with normal screening coagulation tests.

Eva Nourbakhsh¹, Reza Anvari, Nicholas D'cunha

¹Texas Tech University Health Sciences Center, Lubbock, Texas 79416, USA. eva.nourbakhsh@ttuhsc.edu

The American Journal of the Medical Sciences

|August 2, 2011

Summary

This summary is machine-generated.

A patient with unexplained bleeding post-surgery was diagnosed with factor XIII deficiency, a rare coagulation disorder. Treatment with cryoprecipitate effectively stopped the bleeding, highlighting the need for specific factor XIII testing.

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Last Updated: May 30, 2026

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Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

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Published on: December 30, 2025

Area of Science:

Hematology
Coagulation Disorders

Background:

Factor XIII deficiency is a rare inherited or acquired bleeding disorder.
Standard coagulation tests often yield normal results in affected individuals.

Observation:

A male patient presented with persistent drops in hemoglobin, hematocrit, and platelets after trauma surgery.
Initial laboratory workup, including coagulation screens, was unremarkable.

Findings:

Factor XIII antigen levels were significantly reduced (25% of predicted).
Diagnosis of factor XIII deficiency was confirmed.
Treatment with cryoprecipitate led to cessation of bleeding.

Implications:

Factor XIII deficiency should be suspected in cases of unexplained bleeding, particularly post-trauma or surgery.
Specific assays for factor XIII activity or antigen levels are crucial for diagnosis.
Management options include cryoprecipitate, fresh-frozen plasma, or recombinant factor XIII.