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Updated: May 30, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Use of an "antibiotic plate" for infected periprosthetic fracture in total hip arthroplasty
Frank A Liporace1, Richard S Yoon, Matthew A Frank
1Division of Orthopaedic Trauma, Department of Orthopaedic Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA. liporace33@gmail.com
Abstract:
Periprosthetic fracture and infection are dreaded complications after total hip arthroplasty. We present the case of a 50-year-old man who suffered an early postoperative Vancouver B1 periprosthetic fracture, which was further complicated by concurrent infection after open reduction and internal fixation. We report the novel use of an antibiotic-impregnated cement coated locking plate during the staged treatment of concomitant periprosthetic fracture and chronic total hip arthroplasty infection. At 1-year follow-up, the patient is pain free and ambulating independently with full range of motion.
Insights
A 50-year-old man experienced a Vancouver B1 periprosthetic fracture and infection after hip surgery. Treatment involved a novel antibiotic-impregnated cement coated locking plate, leading to a successful recovery.
Area of Science:
- Orthopedic Surgery
- Infectious Disease Management
Background:
- Periprosthetic fractures and infections are significant complications following total hip arthroplasty.
- Early Vancouver B1 periprosthetic fractures pose a challenge, especially when combined with infection.
Observation:
- A 50-year-old male patient developed a Vancouver B1 periprosthetic fracture and concurrent infection post-total hip arthroplasty.
- The initial treatment involved open reduction and internal fixation, which was complicated by infection.
Findings:
- A novel approach utilized an antibiotic-impregnated cement coated locking plate for staged treatment.
- This technique addressed both the periprosthetic fracture and the chronic hip arthroplasty infection simultaneously.
Implications:
- This case demonstrates a potentially effective strategy for managing complex periprosthetic fractures with concurrent infection.
- The use of antibiotic-impregnated implants may improve outcomes in challenging orthopedic cases.
- Successful management resulted in the patient being pain-free and regaining independent ambulation with full range of motion.
