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Published on: April 28, 2013
Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation
Joanna Brydak-Godowska1, Szymon Szczepanik, Michal Ciszek
1Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. joannabg@tlen.pl
Background:
Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.
Case Report:
We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.
Conclusions:
Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.
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