Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coexistence of Y, W, and Z sex chromosomes in Xenopus tropicalis.

Proceedings of the National Academy of Sciences of the United States of America·2015
Same author

Contractile activity is required for Z-disc sarcomere maturation in vivo.

Genesis (New York, N.Y. : 2000)·2015
Same author

An essential role for LPA signalling in telencephalon development.

Development (Cambridge, England)·2014
Same author

Small RNA profiling of Xenopus embryos reveals novel miRNAs and a new class of small RNAs derived from intronic transposable elements.

Genome research·2013
Same author

Efficient high-throughput sequencing of a laser microdissected chromosome arm.

BMC genomics·2013
Same author

A large pseudoautosomal region on the sex chromosomes of the frog Silurana tropicalis.

Genome biology and evolution·2013

Related Experiment Video

Updated: May 30, 2026

Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation
09:48

Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation

Published on: August 21, 2010

Developmental genetics in Xenopus tropicalis.

Timothy J Geach1, Lyle B Zimmerman

  • 1National Institute for Medical Research, London, UK.

Methods in Molecular Biology (Clifton, N.J.)
|August 2, 2011
PubMed
Summary
This summary is machine-generated.

The frog Xenopus tropicalis is a new model for studying tetrapod development, combining genetics with embryology. Its genome is similar to amniotes, aiding genetic research.

More Related Videos

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus
14:50

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus

Published on: January 12, 2015

Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development
09:22

Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development

Published on: February 9, 2015

Related Experiment Videos

Last Updated: May 30, 2026

Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation
09:48

Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation

Published on: August 21, 2010

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus
14:50

Understanding Early Organogenesis Using a Simplified In Situ Hybridization Protocol in Xenopus

Published on: January 12, 2015

Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development
09:22

Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development

Published on: February 9, 2015

Area of Science:

  • Developmental biology
  • Comparative genomics
  • Amphibian genetics

Background:

  • The diploid pipid frog Xenopus tropicalis is emerging as a valuable model organism.
  • It shares developmental similarities with Xenopus laevis, allowing for technique transfer.
  • Its compact genome exhibits high synteny with amniote genomes.

Purpose of the Study:

  • To highlight Xenopus tropicalis as a powerful model system for tetrapod development research.
  • To emphasize the advantages of combining genetic and genomic analyses with embryological and biochemical assays.
  • To showcase the utility of Xenopus tropicalis for genetic approaches.

Main Methods:

  • Utilizing Xenopus tropicalis for genetic and genomic analysis.
  • Employing embryological and biochemical assays.
  • Leveraging haploid genetics and gynogenesis for genetic studies.

Main Results:

  • Xenopus tropicalis facilitates the integration of genetic and genomic studies with traditional biological assays.
  • Its genome's synteny with amniotes enables comparative studies.
  • The ease of haploid genetics and gynogenesis simplifies genetic investigations.

Conclusions:

  • Xenopus tropicalis offers a unique platform for advancing the understanding of tetrapod development.
  • Its genetic tractability and genomic features make it ideal for diverse research applications.
  • This model system bridges amphibian and amniote research fields.