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Related Experiment Videos

Protein-losing enteropathy resolved by percutaneous intervention.

Gianfranco Butera¹, Davide Marini, Simon T MacDonald

¹Pediatric Cardiology and GUCH Unit, Policlinico San Donato, IRCCS, Italy. gianfra.but@lycos.com

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions

|August 2, 2011

Summary

Protein-losing enteropathy (PLE) is a serious complication after total cavopulmonary connection. This study shows percutaneous closure of persistent anterograde pulmonary blood flow successfully treated PLE in a young patient.

Related Experiment Videos

Area of Science:

Cardiology
Pediatric Cardiology
Congenital Heart Disease

Background:

The extracardiac total cavopulmonary connection (TCPC) is a Fontan-type procedure for single-ventricle physiology.
Protein-losing enteropathy (PLE) and plastic bronchitis are severe complications following TCPC.
These complications significantly impact patient outcomes and long-term follow-up.

Observation:

A 16-year-old boy presented with protein-losing enteropathy (PLE) after undergoing a total cavopulmonary connection.
The patient had persistent anterograde pulmonary blood flow, contributing to the development of PLE.
This condition posed a significant risk for early and long-term complications.

Findings:

Successful percutaneous closure of the persistent anterograde pulmonary blood flow was achieved.
An 8-mm Amplatzer Ventricular Septal Defect (VSD) Occluder was utilized for the closure.
The intervention led to the resolution of protein-losing enteropathy in the patient.

Implications:

Percutaneous closure of persistent anterograde pulmonary blood flow is a viable treatment for PLE post-TCPC.
This minimally invasive approach offers a potential solution for managing severe complications of single-ventricle palliation.
Further research is warranted to evaluate the long-term efficacy and safety of this technique.