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Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...

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Updated: May 30, 2026

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
06:59

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

Published on: February 2, 2022

Renal replacement in the deployed setting.

I Nesbitt1, M K Almond, D A Freshwater

  • 1201 (N) Field Hospital (V), Birmingham. ian.nesbitt@nuth.nhs.uk

Journal of the Royal Army Medical Corps
|August 3, 2011
PubMed
Summary

UK military medics successfully used continuous venovenous hemofiltration to treat a soldier with severe injuries and acute renal failure in Afghanistan. This marked a significant advancement in deployed critical care capabilities for British forces.

Area of Science:

  • Military Medicine
  • Critical Care
  • Nephrology

Background:

  • Deployed military operations present unique challenges for managing severe trauma and multi-organ dysfunction.
  • Access to advanced life support, including renal replacement therapy, is often limited in austere environments.
  • Previous limitations in deployed renal replacement therapy capabilities for UK forces necessitated case-by-case evaluations.

Observation:

  • A UK soldier sustained multiple injuries, including a lacerated liver, in Afghanistan.
  • The soldier developed acute anuric renal failure, a life-threatening complication.
  • The patient's condition was stabilized using continuous venovenous hemofiltration (CVVH) prior to medical evacuation.

Findings:

  • Continuous venovenous hemofiltration (CVVH) proved effective in stabilizing a critically injured soldier with acute renal failure in a deployed setting.

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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
06:59

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

Published on: February 2, 2022

  • This represents the first use of renal replacement therapy by UK forces in a deployed operational theatre in decades.
  • The successful application of CVVH highlights the feasibility of providing advanced critical care interventions remotely.

    • Implications:

    • The case demonstrates the potential for advanced renal replacement therapy in deployed military medical settings.
    • It prompts a re-evaluation of the provision and accessibility of high-level critical care capabilities for military personnel serving abroad.
    • Future military medical strategies may need to incorporate advanced life support modalities to improve outcomes for severely injured soldiers.