Related Experiment Video
Updated: May 30, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Prospective memory in schizophrenia and schizotypy.
Julie D Henry1, Peter G Rendell, Phoebe Rogers
1School of Psychology, University of Queensland, St Lucia, Brisbane, Australia. julie.henry@uq.edu.au
Schizophrenia patients show general prospective memory (PM) difficulties, regardless of task demands. This generalized impairment in PM does not support its role as an endophenotype for schizophrenia.
Area of Science:
- Cognitive Psychology
- Neuroscience
- Psychiatry
Background:
- Schizophrenia is often linked to prospective memory (PM) deficits.
- The Multiprocess Framework suggests PM involves automatic and strategic processes influenced by task characteristics like cue saliency.
Purpose of the Study:
- To investigate if prospective memory (PM) impairment in schizophrenia varies with target-cue saliency.
- To examine the relationship between PM and schizotypy, assessing PM as a potential endophenotype.
Main Methods:
- Administered a prospective memory (PM) task with manipulated target-cue saliency to individuals with schizophrenia, matched controls, and low/high schizotypy groups.
- Utilized Virtual Week, a lab-based measure, to assess high and low schizotypy groups further.
Main Results:
- Individuals with schizophrenia demonstrated prospective memory (PM) deficits, irrespective of target-cue saliency.
- No significant differences in prospective memory (PM) performance were found between high and low schizotypy groups.
Conclusions:
- Findings support the view of generalized prospective memory (PM) impairment in schizophrenia.
- The lack of schizotypy effects on PM does not align with the hypothesis of PM as an endophenotype for schizophrenia.
More Related Videos
12:00Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
Published on: November 19, 2014
11:01Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
Published on: August 30, 2011
Related Concept Videos
Schizophrenia
Psychological and Sociocultural Causes of Schizophrenia
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...