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Updated: May 30, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

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The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket

E V Schneider1, J Böttcher, M Blaesse

  • 1Max-Planck-Institut für Biochemie, Am Klopferspitz 18, D-82152 Martinsried, Germany.

Journal of Molecular Biology
|August 3, 2011
PubMed

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