Related Experiment Video
Updated: May 30, 2026

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
Published on: February 23, 2016
Numbers and time doubly dissociate
Marinella Cappelletti1, Elliot D Freeman, Lisa Cipolotti
1Institute of Cognitive Neuroscience, University College London, London, UK. m.cappelletti@ucl.ac.uk
Abstract:
The magnitude dimensions of number, time and space have been suggested to share some common magnitude processing, which may imply symmetric interaction among dimensions. Here we challenge these suggestions by presenting a double dissociation between two neuropsychological patients with left (JT) and right (CB) parietal lesions and selective impairment of number and time processing respectively. Both patients showed an influence of task-irrelevant number stimuli on time but not space processing. In JT otherwise preserved time processing was severely impaired in the mere presence of task-irrelevant numbers, which themselves could not be processed accurately. In CB, impaired temporal estimation was influenced by preserved number processing: small numbers made (already grossly underestimated) time intervals appear even shorter relative to large numbers. However, numerical estimation was not influenced by time in healthy controls and in both patients. This new double dissociation between number and time processing and the asymmetric interaction of number on time: (1) provides further support to the hypothesis of a partly shared magnitude system among dimensions, instead of the proposal of a single, fully shared system or of independent magnitude systems which would not explain dissociations or interactions among dimensions; (2) may be explained in terms of a stable hierarchy of dimensions, with numbers being the strongest.
Related Concept Videos
Double Resonance Techniques: Overview
Spin decoupling is usually achieved by...
¹H NMR: Complex Splitting
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied first.
Interpreting ¹H NMR Signal Splitting: The (n + 1) Rule
¹H NMR Signal Multiplicity: Splitting Patterns
¹³C NMR: ¹H–¹³C Decoupling
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
Tandem Mass Spectrometry

