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Updated: May 30, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Is fatigue associated with suicidality in stroke?

Wai-Kwong Tang¹, Jin-Yan Lu, Vincent Mok

¹Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China. tangwk@cuhk.edu.hk.

Archives of Physical Medicine and Rehabilitation

|August 3, 2011

Summary

Post-stroke fatigue is a significant predictor of suicidal ideation (SI) in Chinese stroke survivors. Early identification and management of fatigue may help reduce suicidal risk in these patients.

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Area of Science:

Neurology
Psychiatry
Public Health

Background:

Stroke is a leading cause of disability worldwide, often associated with significant psychological sequelae.
Post-stroke fatigue is a common and debilitating symptom impacting quality of life.
The relationship between fatigue and suicidal ideation (SI) in stroke patients requires further investigation.

Purpose of the Study:

To evaluate the association between post-stroke fatigue and suicidal ideation (SI) in Chinese patients experiencing their first or recurrent stroke.
To identify fatigue as a potential modifiable risk factor for SI in stroke survivors.

Main Methods:

A cross-sectional survey was conducted with 595 patients admitted to an acute stroke unit in Hong Kong.
Fatigue Severity Scale (FSS) and Geriatric Mental State Examination were used to assess fatigue and SI, respectively, at 3 months post-stroke.
Logistic regression analysis adjusted for confounders including age, sex, depression, and stroke severity (NIHSS).

Main Results:

12.8% of patients reported SI.
Patients with SI had significantly higher Fatigue Severity Scale scores compared to those without SI (4.0±1.4 vs 2.8±1.2).
Fatigue Severity Scale score was a significant independent predictor of SI (odds ratio=1.5), even after adjusting for confounders.

Conclusions:

Post-stroke fatigue is strongly associated with suicidal ideation in Chinese stroke patients.
Clinicians should be vigilant in assessing and managing fatigue in stroke survivors.
Early intervention for fatigue may play a crucial role in mitigating suicidal risk.