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Updated: May 30, 2026
09:31
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Small renal masses: toward more rational treatment
Anil A Thomas1, Steven C Campbell
1Glickman Urological and Kidney Institute, Cleveland, OH 44195, USA.
Cleveland Clinic Journal of Medicine
|August 3, 2011
Summary
Managing small renal masses is complex. Partial nephrectomy is preferred, with thermal ablation or active surveillance as alternatives, while renal mass biopsy and molecular profiling may guide future treatments.
Area of Science:
- Urology
- Oncology
- Nephrology
Background:
- Small renal masses present a frequent clinical challenge with evolving treatment paradigms.
- Radical nephrectomy remains common, but less invasive options are gaining prominence.
Purpose of the Study:
- To review current and emerging strategies for managing small renal masses.
- To highlight the shift towards nephron-sparing approaches and personalized medicine.
Main Methods:
- Review of current literature on small renal mass management.
- Discussion of established and investigational treatment modalities.
Main Results:
- Partial nephrectomy is increasingly recognized as the preferred surgical approach.
- Thermal ablation and active surveillance are viable options for select patient groups.
- Renal mass biopsy with molecular profiling shows promise for tailored treatment decisions.
Conclusions:
- The management of small renal masses requires individualized treatment planning.
- Future directions emphasize precision medicine through biopsy and molecular analysis for optimal patient outcomes.
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