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Constipation in childhood

Suzanne M Mugie1, Carlo Di Lorenzo, Marc A Benninga

  • 1Emma Children's Hospital, Amsterdam Medical Center, Meigbergdreef 9, Amsterdam, 1105 AZ, The Netherlands.

Nature Reviews. Gastroenterology & Hepatology
|August 3, 2011
PubMed

Insights

Childhood constipation, a common pediatric functional gastrointestinal disorder, often stems from stool withholding after painful bowel movements. Diagnosis relies on history, physical exam, and bowel diary, with standard treatment involving education, toilet training, and medication.

Area of Science:

  • Pediatric Gastroenterology
  • Functional Gastrointestinal Disorders

Background:

  • Childhood constipation is a prevalent, long-lasting pediatric functional gastrointestinal disorder.
  • Affects 0.7%–29.6% globally, with significant healthcare costs.
  • Pathophysiology is multifactorial, commonly initiated by stool withholding after painful experiences.

Purpose of the Study:

  • To review current knowledge on childhood constipation.
  • To emphasize the latest data on pathogenesis, diagnosis, and treatment.
  • To provide an overview of clinical aspects.

Main Methods:

  • Comprehensive review of existing literature.
  • Synthesis of data on epidemiology, pathophysiology, diagnosis, and treatment.
  • Focus on recent clinical trials and outcome studies.

Main Results:

  • Diagnosis is typically achieved through medical history, physical examination, and bowel diary.
  • Standard treatment includes education, toilet training, disimpaction, maintenance therapy, and follow-up.
  • Recent advancements in treatment trials and long-term outcome studies are available.

Conclusions:

  • Childhood constipation requires a multifactorial approach to management.
  • Current standard treatments are effective when implemented comprehensively.
  • Ongoing research continues to refine understanding and treatment strategies.

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