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Published on: February 14, 2011
Disseminated histoplasmosis with conjunctival involvement in an immunocompromised patient
Arun Shirali1, Jyoti Kini, Anjith Vupputuri
1Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.
Abstract:
We report a case of disseminated histoplasmosis in a 37-year-old male acquired immunodeficiency syndrome patient from south India. The patient presented with high-grade fever, cough, conjunctival nodule and papulonodular hyperpigmented skin lesions. Histology of skin lesions and conjunctival nodule showed numerous intracellular Periodic Acid Schiff-positive rounded yeast cells within macrophages. Bone marrow aspirate confirmed disseminated histoplasmosis. The patient showed dramatic response after starting treatment with Amphotercin B.
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