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Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
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Related Experiment Video

Updated: May 30, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
26:48

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

Subacute sclerosing panencephalitis presenting as mania.

Ashish Aggarwal1, Ashish Khandelwal, Manish Jain

  • 1Department of Psychiatry, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Annals of Indian Academy of Neurology
|August 3, 2011
PubMed
Summary
This summary is machine-generated.

Subacute sclerosing panencephalitis (SSPE), a fatal neurological disease after measles, can rarely present with psychiatric symptoms. This case highlights the importance of considering organic causes, like SSPE, in patients with unusual psychiatric presentations.

Keywords:
Manic episodeperiodic complexsubacute sclerosing panencephalitis

Related Experiment Videos

Last Updated: May 30, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
26:48

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

Area of Science:

  • Neurology
  • Infectious Diseases
  • Psychiatry

Background:

  • Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal neurological disorder.
  • It is a late complication of measles virus infection, typically affecting children and young adults.
  • While neurological deficits are common initial symptoms, atypical presentations are occasionally reported.

Observation:

  • A 14-year-old male presented with initial symptoms of mania.
  • Diagnostic workup revealed the patient was suffering from subacute sclerosing panencephalitis (SSPE).
  • This case underscores the diverse clinical manifestations of SSPE.

Findings:

  • The patient's manic symptoms preceded the development of overt neurological signs of SSPE.
  • This presentation challenges the typical understanding of SSPE's initial clinical course.
  • Early diagnosis of SSPE is crucial despite atypical initial symptoms.

Implications:

  • Physicians must consider rare organic neurological conditions like SSPE in the differential diagnosis of new-onset psychiatric symptoms.
  • Prompt investigation can lead to earlier diagnosis and management of SSPE.
  • Recognizing psychiatric presentations of SSPE is vital for improving patient outcomes and understanding disease pathophysiology.