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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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[Strategies to improve medication adherence].

U Laufs1, M Böhm, H K Kroemer

  • 1Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar. ulrich@laufs.com

Deutsche Medizinische Wochenschrift (1946)
|August 3, 2011
PubMed
Summary
This summary is machine-generated.

Many patients with chronic diseases struggle with medication adherence, impacting health outcomes. Interventions like patient counseling and simplified dosing can improve adherence, but more research is needed.

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Area of Science:

  • Pharmacology
  • Health Services Research
  • Patient Care

Background:

  • Up to 50% of patients with chronic diseases exhibit poor medication adherence.
  • Non-adherence to drug therapy significantly increases morbidity and mortality rates.

Purpose of the Study:

  • To review evidence-based strategies for improving medication adherence.
  • To identify research gaps, particularly within the German healthcare system.

Main Methods:

  • A selective literature search was conducted using keywords such as adherence, compliance, concordance, persistence, medication management, and pharmaceutical care.
  • Evidence for interventions like individual patient counseling, simplified dosing regimens, combination tablets, and unit doses (e.g., blister cards) was evaluated.

Main Results:

  • Individual counseling, simplified dosing, and unit doses demonstrated effectiveness in improving medication adherence.
  • The demonstrated effectiveness of these interventions was limited to the duration of the intervention period.
  • Prospective clinical evaluations with defined clinical endpoints are lacking, especially for the German healthcare system.

Conclusions:

  • Improving medication adherence is crucial for patient outcomes and cost reduction, potentially as significant as developing new therapies.
  • Further research, including prospective clinical trials, is necessary to establish best practices and develop clinical recommendations.
  • Collaborative efforts between physicians and pharmacists are essential for enhancing medication adherence.