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Updated: May 30, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Pathogenetic characteristics of generalized parodontitis in elderly patients]
Abstract:
Chronic periodontit inflammation in old-aged patients was found to be accompanied by imbalance of complement system; sIgA, IgA, IgG and IgM hyperproduction; increased concentrations of IL-8, IL-1alpha and decreased level of IL-4; abrogated NO and its derivatives concentration; increased anti-HSP-70 and homocystein levels in blood and saliva. The obtained results justify the necessity to use in therapy of chronic parodontit inflammation the immunocorrection, antioxidant and bioregulatory therapy, which normalize the cells function.
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