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Updated: May 30, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Abstract:
Our data on treatment of renal carcinoma in 12 children (1996-2006) are presented. Nephrectomy and lymph node dissection was carried out in all patients; adjuvant chemotherapy (doxorubicin, interferon alpha2b (IBF alpha2b/Intron A) with concomitant whole body hyperthermia (systemic thermobiochemotherapy--7. Overall 10-year survival in all patients was 91% (median 42.3 months). Survival rate in cases of advanced renal carcinoma who received postoperative thermobiochemotherapy was 86% (median 54.8 months). Our results suggest that thermobiochemotherapy be indicated in children with advanced renal carcinoma.
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