Ellen R. Grass lecture: Back to the future: from grass roots to microchips

Area of Science:

• Clinical Neurophysiology
• Biomedical Engineering
• Neuroscience

Background:

• The field of clinical neurophysiology (CNP) has undergone substantial evolution over the past seven decades.
• Pioneers like Ellen Grass and numerous technologists have been crucial in translating CNP advancements into practical clinical applications.

Observation:

• Key technological developments include long-term EEG/video ICU monitoring, intraoperative monitoring, high-frequency oscillation (HFO) recordings, automated signal analysis, and seizure prediction.
• Research into implanted intracranial recording and stimulation devices represents a significant frontier.

Findings:

• These technological advancements enhance our fundamental understanding of nervous system function.
• The ultimate aim is to translate these evolving technologies for superior patient care and outcomes.

Implications:

• Professional organizations like ABRET and ASET are vital for guiding the ethical application and standardization of CNP technology.
• The field is experiencing a resurgence, moving beyond early Grass EEG machines towards advanced microchip-based intracranial devices, indicating a promising future.