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Published on: August 15, 2025
Food-derived oligosaccharides exhibit pharmaceutical properties
Anneke Rijnierse1, Prescilla V Jeurink, Betty C A M van Esch
1Department of Immunology, Danone Research-Centre for Specialised Nutrition, Wageningen, The Netherlands. anneke.rijnierse@danone.com
Human milk oligosaccharides offer nutritional benefits for infant growth and development. These compounds also show promising direct effects on the infant immune system, warranting further study.
Area of Science:
- Nutritional Science
- Immunology
- Microbiology
Background:
- Breastfeeding provides optimal infant nutrition.
- Human milk contains unique components like oligosaccharides.
- Oligosaccharides are known to modulate gut microbiota and emerging evidence suggests immune effects.
Purpose of the Study:
- To review the pharmaceutical properties of food-borne oligosaccharides.
- To summarize the benefits of oligosaccharides for infant health and immunity.
Main Methods:
- Literature review of scientific studies on oligosaccharides.
- Analysis of research on oligosaccharide effects on infant gut bacteria and immune responses.
Main Results:
- Oligosaccharides selectively promote beneficial gut bacteria.
- Evidence indicates direct immunomodulatory effects of oligosaccharides.
- Food-derived oligosaccharides are used as supplements for health benefits.
Conclusions:
- Oligosaccharides are crucial components of early life nutrition.
- These compounds possess significant pharmaceutical properties impacting infant immunity.
- Further research into food-borne oligosaccharides is essential for optimizing infant health.
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