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Updated: May 30, 2026

High-Resolution Fluoro-Respirometry of Equine Skeletal Muscle
Published on: February 3, 2023
Equine rhabdomyolysis
E M Quist1, J J Dougherty, M K Chaffin
1Department of Veterinary Pathobiology, Texas Veterinary Medical Center, 4467 TAMU, College Station, TX 77843-4467, USA. equist@cvm.tamu.edu
Abstract:
A 1.5-year-old Quarter Horse gelding with a history of chronic nasal discharge and leukocytosis presented with signs of increased lethargy and muscular pain. The horse quickly became recumbent and unable to rise and was euthanized due to a poor prognosis. At necropsy, severe bilateral guttural pouch empyema was observed, as well as numerous well-demarcated areas of pallor within the skeletal muscles of all major muscle groups. Polymerase chain reaction testing of the guttural pouch exudate confirmed an infection with Streptococcus equi subsp. equi, and an S. equi-associated immune-mediated rhabdomyolysis was initially considered to be the most likely diagnosis. This report briefly discusses the various etiologies that should be considered in cases of equine myopathy, and it demonstrates the complexity of these poorly understood muscular disorders.
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