Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...

Diels–Alder Reaction: Characteristics of Dienes

Diels–Alder Reaction: Characteristics of Dienes

The Diels–Alder reaction brings together a diene and a dienophile to form a six-membered ring. Both components have unique characteristics that influence the rate of the reaction.
Characteristics of the diene
Conformation
The simplest example of a diene is 1,3-butadiene, an acyclic conjugated π system. At room temperature, the molecule exists as a mixture of s-cis and s-trans conformers by virtue of rotation around the carbon–carbon single bond. Although the s-trans isomer is more stable, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An augmented evidence base for the interpretation of forensic text-based communications materials as intelligence and evidence.

Forensic science international. Synergy·2026

Same author

Population genetic screening efficiently identifies carriers of autosomal dominant diseases.

Nature medicine·2020

Same author

Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects.

Journal of internal medicine·2020

Same author

Stem cells and physical energies: can we really drive stem cell fate?

Physiological research·2020

Same author

Elucidating the Effect of Static Electric Field on Amyloid Beta 1-42 Supramolecular Assembly.

Journal of molecular graphics & modelling·2020

Same author

Dominant effect of relative tropical Atlantic warming on major hurricane occurrence.

Science (New York, N.Y.)·2018

Search research articles

Related Experiment Video

Updated: May 30, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

Catalytic chameleon dendrimers.

M Shema-Mizrachi¹, G M Pavan, E Levin

¹Department of Chemistry, Ben-Gurion University, Beer-Sheva, Israel.

Journal of the American Chemical Society

|August 5, 2011

Summary

This summary is machine-generated.

Iron porphyrin dendrimers with tunable boronic ester termini were synthesized. Changing the end-groups altered their shape and significantly impacted catalytic epoxidation activity and selectivity for various alkenes.

More Related Videos

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Related Experiment Videos

Last Updated: May 30, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Published on: September 10, 2013

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Published on: December 4, 2016

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Area of Science:

Supramolecular Chemistry
Catalysis
Materials Science

Background:

Dendrimers offer unique nanoscale architectures with tunable properties.
Iron porphyrin complexes are known for their catalytic activity.
Controlling dendrimer properties through terminal group modification is an active research area.

Purpose of the Study:

To synthesize and characterize novel dendrimers featuring an iron porphyrin core and boronic ester end-groups.
To investigate the reversible exchange of dendrimer termini using diol molecules.
To explore the impact of terminal group modification on catalytic performance, specifically in epoxidation reactions.

Main Methods:

Synthesis and characterization of iron porphyrin dendrimers.
Reversible terminal group exchange using diols.
Molecular dynamics (MD) simulations to study conformational changes.
Evaluation of catalytic activity and selectivity in alkene epoxidation.

Main Results:

Successful synthesis and characterization of the target dendrimers.
Demonstration of reversible terminal group exchange.
MD simulations revealed that terminus exchange alters dendrimer conformation and end-group positioning.
Catalytic epoxidation activity and selectivity were significantly affected by the spatial arrangement of the termini.

Conclusions:

The study demonstrates a novel method for controlling dendrimer catalytic behavior by reversibly modifying terminal groups.
Tunable steric environments around the iron porphyrin core can be achieved, influencing reaction outcomes.
This approach offers a new strategy for designing advanced catalysts with adjustable performance.