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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: May 30, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Migraine with binocular blindness: a clinic-based study.

¹Department of Neurology, Geisinger Wyoming Valley, Wilkes-Barre, PA, USA. tdrozmigraine@yahoo.com

|August 5, 2011

Summary

Binocular blindness during migraine is rare, affecting 1.6% of patients. This condition predominantly impacts women and may indicate an underlying clotting disorder, warranting further investigation.

Area of Science:

Neurology
Ophthalmology

Background:

Migraine patients rarely report bilateral blindness during headache attacks.
Limited research exists on the prevalence, demographics, and diagnostic findings of binocular blindness in migraine.

Observation:

A study at a headache center identified 6 patients (1.6%) with binocular blindness during migraine.
All affected patients were female, with a history of migraine for at least 3 years, often without aura.

Findings:

Episodes of binocular blindness varied in duration and frequency, occurring in isolation during headaches.
Neuroimaging was normal in all patients, but coagulopathy testing was abnormal in all.
Abnormalities included MTHFR polymorphisms and a positive lupus anticoagulant in one patient.

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Last Updated: May 30, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Published on: June 2, 2014

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Implications:

Binocular blindness in migraine is a rare, female-predominant event, potentially linked to coagulopathies.
The etiology may involve clotting disorders or retinal spreading depression, necessitating further research.