Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares often...
Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insights into the occurrence and biotoxicity impact of zinc oxide nanoparticles within healthcare and sanitary products.

Talanta·2026
Same author

Surface plasmon resonance optical sensors involving nanomaterials as reliable analytical tools: A critical view about performance and applications.

Analytica chimica acta·2025
Same author

Corrigendum: Biomarkers of response to ocrelizumab in relapsing-remitting multiple sclerosis.

Frontiers in immunology·2025
Same author

Biomarkers of response to ocrelizumab in relapsing-remitting multiple sclerosis.

Frontiers in immunology·2024
Same author

Response surface methology for enzymatic ultrasound assisted sp-ICP-MS assessment of cuonps in seafood: Occurrence and bioaccumulation.

Food chemistry·2024
Same author

γ-Cyclodextrin-graphene quantum dots-chitosan modified screen-printed electrode for sensing of fluoroquinolones.

Mikrochimica acta·2023

Related Experiment Video

Updated: May 30, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

Sleep disturbances in multiple sclerosis.

Ana Caminero1, Manuel Bartolomé

  • 1Multiple Sclerosis Unit, Department of Neurology, Complejo Asistencial de Ávila, Spain. acaminero@saludcastillayleon.es

Journal of the Neurological Sciences
|August 5, 2011
PubMed
Summary

Sleep disturbances are common in multiple sclerosis (MS) and significantly impact patients

Area of Science:

  • Neurology
  • Sleep Medicine

Background:

  • Sleep disturbances are frequently underestimated in multiple sclerosis (MS).
  • These disturbances significantly affect the quality of life for MS patients.
  • There is a bidirectional relationship between MS and sleep disturbances.

Purpose of the Study:

  • To review common sleep disorders in MS patients.
  • To discuss prevalence, pathophysiology, clinical manifestations, and treatments.
  • To analyze the relationship between sleep disturbances and chronic fatigue in MS.

Main Methods:

  • Review of epidemiological data on sleep disturbances in MS.
  • Analysis of specific sleep disorders: insomnia, circadian rhythm disorders, RLS, PLM, sleep-related respiratory disorders, narcolepsy-cataplexy, RBD.

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

Related Experiment Videos

Last Updated: May 30, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

  • Examination of how sleep disturbances increase morbidities and interact with MS progression.

    • Main Results:

    • Sleep disturbances are more prevalent in MS patients compared to the general population.
    • Various dyssomnias and parasomnias are commonly observed in MS.
    • Sleep disturbances are linked to increased comorbidities and chronic fatigue in MS.

    Conclusions:

    • Sleep disturbances are a significant issue in MS, impacting quality of life.
    • These sleep problems warrant focused attention within multidisciplinary MS care.
    • Addressing sleep disturbances is crucial for comprehensive MS management.