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Updated: May 30, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Anaemia in low-income and middle-income countries
Yarlini Balarajan1, Usha Ramakrishnan, Emre Ozaltin
1Department of Global Health and Population, Harvard School of Public Health, Boston, MA 02115-6096, USA.
Insights
Anaemia impacts millions globally, especially children and women, causing significant economic losses. Addressing its complex causes through research and improved strategies is crucial for low-resource settings.
Area of Science:
- Public Health
- Global Health
- Epidemiology
Background:
- Anaemia affects a quarter of the global population, with high prevalence in children and non-pregnant women.
- The economic impact of anaemia on human capital results in billions of dollars in annual losses.
- Anaemia disproportionately affects low socioeconomic groups, highlighting health disparities.
Purpose of the Study:
- To review the epidemiology, clinical assessment, pathophysiology, and consequences of anaemia in low- and middle-income countries.
- To analyze the socioeconomic determinants and risk factors associated with anaemia.
- To identify challenges and propose strategies for alleviating the anaemia burden in resource-limited settings.
Main Methods:
- Literature review of anaemia epidemiology and consequences.
- Analysis of population-level data on anaemia prevalence and risk factors.
- Synthesis of information on multifactorial causes and socioeconomic influences.
Main Results:
- Anaemia is highly prevalent in low-income and middle-income countries, particularly among young children and non-pregnant women.
- Maternal anaemia is strongly linked to child anaemia, indicating intergenerational effects.
- The causes of anaemia are multifactorial, involving complex interactions between nutrition, infectious diseases, and socioeconomic status.
Conclusions:
- Addressing the anaemia burden requires understanding its complex, multifactorial etiology and socioeconomic determinants.
- Improved implementation of population-level strategies and reduction of knowledge gaps in research and policy are essential.
- Targeted interventions are needed to alleviate anaemia, especially in vulnerable populations within low-resource settings.
Abstract:
Anaemia affects a quarter of the global population, including 293 million (47%) children younger than 5 years and 468 million (30%) non-pregnant women. In addition to anaemia's adverse health consequences, the economic effect of anaemia on human capital results in the loss of billions of dollars annually. In this paper, we review the epidemiology, clinical assessment, pathophysiology, and consequences of anaemia in low-income and middle-income countries. Our analysis shows that anaemia is disproportionately concentrated in low socioeconomic groups, and that maternal anaemia is strongly associated with child anaemia. Anaemia has multifactorial causes involving complex interaction between nutrition, infectious diseases, and other factors, and this complexity presents a challenge to effectively address the population determinants of anaemia. Reduction of knowledge gaps in research and policy and improvement of the implementation of effective population-level strategies will help to alleviate the anaemia burden in low-resource settings.
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