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Related Experiment Video

Updated: May 30, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
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Published on: August 24, 2018

Splint sterilization--a potential registration hazard in computer-assisted surgery.

Michael Figl1, Christoph Weber, Ojan Assadian

  • 1Center for Biomedical Engineering and Physics, Medical University Vienna, Vienna, Austria.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
|August 5, 2011
PubMed
Summary

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Hydrogen peroxide plasma sterilization effectively sterilizes navigation splints without causing significant deformation, ensuring accuracy in computer-assisted surgery. This method is safe for thermolabile splints used in surgical navigation.

Area of Science:

  • Medical Imaging
  • Surgical Technology
  • Sterilization Science

Background:

  • Accurate preoperative targeting is vital for computer-assisted surgery.
  • Acrylic splints are commonly used for point-to-point registration.
  • Standardized sterilization protocols for navigation splints are lacking.

Purpose of the Study:

  • To evaluate the deformation of acrylic navigation splints after hydrogen peroxide-based plasma sterilization.
  • To assess the impact of sterilization on the accuracy of surgical navigation.

Main Methods:

  • Acrylic navigation splints with metallic markers were subjected to 5 cycles of hydrogen peroxide plasma sterilization.
  • Computed tomography (CT) scans were acquired before and after sterilization.
  • Image processing quantified splint deformation using registration errors and Hausdorff distances.

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  • Sterilization effectiveness was confirmed using Geobacillus stearothermophilus indicators.

    • Main Results:

    • Mean fiducial registration error was 0.74 mm; target registration error was 0.15 mm.
    • Maximal splint deformation (Hausdorff distance) was 2.51 mm.
    • Sterilization was effective, with no bacterial growth detected.

    Conclusions:

    • Hydrogen peroxide-based low-temperature plasma sterilization does not cause significant deformation in acrylic navigation splints.
    • This sterilization method preserves splint integrity, supporting accurate computer-navigated surgery.