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Vasopressin: Its current role in anesthetic practice
Jayanta K Mitra1, Jayeeta Roy, Saikat Sengupta
1Departments of Anaesthesiology, College of Medicine and JNM Hospital, Kalyani, Nadia, India.
Vasopressin, an endogenous hormone regulating fluid balance, also acts as a neurotransmitter and raises blood pressure. Its therapeutic uses in critical care, including septic shock and cardiac arrest, are expanding.
Area of Science:
- Endocrinology
- Neuroscience
- Critical Care Medicine
Background:
- Vasopressin (antidiuretic hormone) is a key endogenous hormone.
- It regulates plasma osmolality and volume.
- It functions as a neurotransmitter influencing circadian rhythm, thermoregulation, and hormone release.
Purpose of the Study:
- To review the expanding therapeutic applications of vasopressin.
- To highlight its role in critical care settings.
- To discuss its potential as a vasopressor agent.
Main Methods:
- Literature review of vasopressin's physiological roles.
- Analysis of clinical applications in critical care.
- Evaluation of its use in shock and cardiac arrest.
Main Results:
- Vasopressin regulates fluid balance and blood pressure.
- It has critical care applications including diabetes insipidus, bleeding, and shock.
- Research over 10 years supports its role as a vasopressor.
Conclusions:
- Vasopressin is a vital hormone with diverse physiological functions.
- Its therapeutic utility in critical care is well-established and growing.
- It is recognized as a valuable vasopressor agent for severe shock and cardiac arrest.
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