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Updated: May 30, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
A new flavonoid and other constituents from Centaurea nicaeensis All. var. walliana M
Leila Hammoud1, Ramdane Seghiri, Samir Benayache
1Laboratoire de Phytochimie et Analyses Physico-Chimiques et Biologiques, Université Mentouri, Route de Aïn El Bey, 25 000 Constantine, Algeria.
Abstract:
A new flavone glucoside, apigenin 4'-(6″-methylglucuronide) (1), together with six known compounds, cirsilineol, jaceosidin, melitensin, apigenin, apigenin 7-(6″-methylglucuronide) and prunasin, were isolated from the ethanolic extract of the aerial parts of Centaurea nicaeensis All. var. walliana M. (Asteraceae) collected from Souk-Ahras, eastern Algeria. The structures were established by spectral analysis, mainly HRESI-MS, UV and 2D-NMR experiments (COSY, HSQC and HMBC).
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