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Unilateral Pyramidotomy of the Corticospinal Tract in Rats for Assessment of Neuroplasticity-inducing Therapies
Published on: December 15, 2014
Partial recovery from amnesia following bilateral surgical fornix transection is correlated with cortical plasticity
N K Mazarakis1, F Summers, A D Murray
1Department of Neurosurgery, Queen's Medical Centre, Nottingham, UK. nm1@doctors.org.uk
British Journal of Neurosurgery
|August 6, 2011
Abstract:
We report a case of an interventricular ependymoma which was surgically removed but also required bilateral transection of the fornices resulting in memory impairment which gradually improved. Functional MR images using a memory paradigm showed that recovery correlated with cortical plasticity involving activation of the orbitofrontal cortex and the middle temporal gyrus.
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