Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Influences on Intelligence01:30

Biological Influences on Intelligence

Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter more...
Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
Environmental Influences on Intelligence01:29

Environmental Influences on Intelligence

Despite the strong genetic influence on traits like intelligence, environmental factors significantly shape outcomes. For example, while over 90% of height variation is due to genetic differences, environmental factors such as nutrition also have a notable impact. Similarly, for intelligence, changes in a child's surroundings can significantly alter their IQ. Research shows that enriched environments boost children's academic success and help them develop key cognitive skills. Children from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HR3/RORα-mediated cholesterol sensing regulates TOR signaling.

Nature communications·2026
Same author

Remote control of AMPK via extracellular adenosine controls tissue growth.

Nature cell biology·2025
Same author

The tumor suppressor CYLD acts as a deubiquitinase for mTOR to constrain its activity.

bioRxiv : the preprint server for biology·2025
Same author

mTORC1 senses glutamine and other amino acids through GCN2.

The EMBO journal·2025
Same author

Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control in HeLa cells.

eLife·2025
Same author

Signals from the niche promote distinct modes of translation initiation to control stem cell differentiation and renewal in the Drosophila testis.

PLoS biology·2025

Related Experiment Video

Updated: May 30, 2026

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)
10:47

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)

Published on: March 2, 2018

Privileged signaling for brain growth.

Aurelio A Teleman1

  • 1German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany. a.teleman@dkfz-heidelberg.de

Cell
|August 6, 2011
PubMed
Summary

During nutrient restriction, the brain continues growing. A new study identifies Alk kinase as crucial for this growth in Drosophila, bypassing insulin receptor and TOR signaling.

Area of Science:

  • Developmental biology
  • Cell signaling
  • Neuroscience

Background:

  • Nutrient restriction typically halts tissue growth in developing animals.
  • The brain is an exception, maintaining growth even under limited nutrients.

Discussion:

  • Cheng et al. (2011) investigated the molecular mechanisms enabling continued brain growth during nutrient scarcity.
  • The study focused on Drosophila melanogaster as a model organism.

Key Insights:

  • Alk kinase was identified as a key regulator of brain growth under nutrient restriction.
  • Alk bypasses the need for insulin receptor and Target of Rapamycin (TOR) pathway activation.

Outlook:

  • This finding sheds light on nutrient-sensing mechanisms in brain development.

More Related Videos

The Use of the Puzzle Box as a Means of Assessing the Efficacy of Environmental Enrichment
06:50

The Use of the Puzzle Box as a Means of Assessing the Efficacy of Environmental Enrichment

Published on: December 29, 2014

Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization
05:35

Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization

Published on: April 19, 2017

Related Experiment Videos

Last Updated: May 30, 2026

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)
10:47

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs)

Published on: March 2, 2018

The Use of the Puzzle Box as a Means of Assessing the Efficacy of Environmental Enrichment
06:50

The Use of the Puzzle Box as a Means of Assessing the Efficacy of Environmental Enrichment

Published on: December 29, 2014

Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization
05:35

Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization

Published on: April 19, 2017

  • Understanding Alk's role could inform strategies for conditions involving growth regulation.