Related Experiment Video

Updated: May 30, 2026

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
06:45

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

Conundra of the penumbra and acute stroke imaging

Magdy H Selim1, Carlos A Molina

  • 1Beth Israel Deaconess Medical Center, Stroke Division, 330 Brookline Avenue, Palmer 127, Boston, MA 02215, USA. mselim@bidmc.harvard.edu

Stroke
|August 6, 2011
PubMed
Abstract

No abstract available in PubMed .

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...