Related Experiment Video
Updated: May 30, 2026

Assessment of Hippocampal Dendritic Complexity in Aged Mice Using the Golgi-Cox Method
Published on: June 22, 2017
[Gogi (word-meaning) aphasia]
1Tohoku University Graduate School of Medicine. dfckf900@kcc.zaq.ne.jp
Abstract:
Gogi (word meaning) aphasia is an aphasic syndrome originally described by Tsuneo Imura in 1943. According to Imura, this syndrome is characterized by 4 symptoms: (1) difficulty in comprehending the meaning of a word despite perfect perception of the sound of the word; (2) presence of word amnesia and verbal paraphasia; (3) preservation of the ability to repeat spoken words; and (4) characteristic disturbances in reading and writing, in which Kana (Japanese syllabogram) can be correctly read and written, but Kanji (Japanese logogram) is read and transcribed in a peculiar way without comprehension, resulting in strange paragraphia. Gogi aphasia occupies a unique seat in the category of transcortical sensory aphasia. While the latter is grossly defined as fluent sensory aphasia with good repetition and without any specification about the linguistic level of deficit, the former is defined more specifically as fluent sensory aphasia with the deficit limited to the level of words. The characteristic Kana-Kanji dissociation aids in the diagnosis of this syndrome. Recently, it has been repeatedly confirmed that the temporal lobe type of Pick disease (known as semantic dementia in recent English literature) often presents the clinical picture of Gogi aphasia in its early course. Many Japanese physicians have contributed to the elucidation of this clinicopathological correlation. This is mainly because many neurologists and psychiatrists in Japan have long been familiar with the concept of Gogi aphasia and the nosology of Pick disease.
Related Concept Videos
Golgi Apparatus
Golgi Apparatus
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
Golgi Apparatus
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
Golgi Matrix Proteins
One of the first identified Golgi matrix proteins was GM130, a rod-like protein located in the cis-Golgi. Subsequently, many Golgi...
Higher Mental Functions of the Brain: Language
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Transport Across the Golgi
