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Related Experiment Video

Updated: May 30, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
08:29

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

Optically controlled thermal management on the nanometer length scale.

F Garwe1, U Bauerschäfer, A Csaki

  • 1Institute of Photonic Technology (IPHT) Jena, PO Box 100239, D-07745 Jena, Germany.

Nanotechnology
|August 6, 2011
PubMed
Summary
This summary is machine-generated.

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Researchers demonstrate precise, localized heating of nanoparticles using laser pulses. This breakthrough enables controlled nanoscale manipulation of materials and biological molecules for advanced applications in nanotechnology and medicine.

Area of Science:

  • Nanotechnology
  • Biotechnology
  • Laser-Matter Interactions

Background:

  • Laser-based manipulation of polymers and biomolecules offers potential in nanotechnology and medicine.
  • Controlled nanoscale heat conversion using laser light on metal nanoparticles can create tools like nanoreactors or nanowelding devices.

Purpose of the Study:

  • To theoretically and experimentally investigate laser radiation interaction with gold nanoparticles on PMMA.
  • To demonstrate highly localized, regulated heat insertion into nanoparticles without ablation.
  • To explore femtosecond laser irradiation of nanoparticles on DNA for localized destruction effects.

Main Methods:

  • Utilized one-photon excitation of gold nanoparticles on polymethylmethacrylate (PMMA) with varying laser pulse lengths, wavelengths, and repetition rates.

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Fabrication and Testing of Photonic Thermometers
08:44

Fabrication and Testing of Photonic Thermometers

Published on: October 24, 2018

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Last Updated: May 30, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices
08:29

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

Fabrication and Testing of Photonic Thermometers
08:44

Fabrication and Testing of Photonic Thermometers

Published on: October 24, 2018

  • Employed femtosecond laser irradiation with single- and two-photon excitation on gold and silver-enhanced gold nanoparticles attached to DNA.
  • Investigated localized heat effects within a 40 nm range.

    • Main Results:

    • Achieved highly local (40 nm) regulated heat insertion into nanoparticles without ablation.
    • Demonstrated localized destruction of DNA near nanoparticles using femtosecond laser irradiation.
    • Showcased the potential for precise nanoscale material and biological molecule manipulation.

    Conclusions:

    • Laser irradiation of nanoparticles offers a novel method for controlled nanoscale thermal effects.
    • This technique holds promise for applications in molecular medicine, nanotechnology, and chemistry.
    • Localized DNA destruction near nanoparticles opens avenues for targeted molecular interventions.