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Systolic blood pressure control after participation in a hypertension intervention study
Lesley K Welch1, Kari L Olson, Karen E Snow
1Denver, CO 80220, USA. Lesley.welch@va.gov
Insights
Systolic blood pressure control was not sustained after a hypertension intervention. Many patients in both intervention and usual care groups experienced uncontrolled blood pressure post-study.
Area of Science:
- Cardiovascular Medicine
- Clinical Hypertension Research
- Public Health Interventions
Background:
- Hypertension management requires sustained blood pressure (BP) control.
- Multimodal interventions aim to improve BP control in patients with uncontrolled hypertension.
- Long-term maintenance of BP control after interventions is not well-established.
Purpose of the Study:
- To evaluate the long-term maintenance of systolic blood pressure (SBP) control after a multimodal hypertension intervention.
- To compare sustained SBP control between an intervention group and usual care (UC) group post-randomized trial.
Main Methods:
- Retrospective cohort study of patients completing the "Improving Blood Pressure in Colorado" randomized trial.
- Chart review to assess the first SBP measurement during routine care after study completion.
- Comparison of proportions with uncontrolled SBP during follow-up among those with controlled SBP at the final study visit.
Main Results:
- Of 283 patients, 51.5% (intervention) and 46.9% (UC) had controlled SBP at the study's end.
- Following the study, 37.0% (intervention) and 46.4% (UC) of patients with prior controlled SBP had uncontrolled SBP.
- No significant difference in time to uncontrolled SBP between the intervention and UC groups.
Conclusions:
- Systolic blood pressure control was not consistently maintained in a significant proportion of patients after completing the hypertension intervention study.
- Findings highlight the need for interventions focusing on long-term BP management beyond the typical short duration of clinical trials.
- Sustained BP control remains a challenge, necessitating further research into long-term strategies for hypertension management.
Objective:
To evaluate whether systolic blood pressure (SBP) control is maintained following participation in a multimodal hypertension intervention.
Study Design:
This was a retrospective cohort of patients completing the Improving Blood Pressure in Colorado study, a randomized trial comparing a multimodal intervention with usual care for patients who had uncontrolled hypertension. Chart review assessed the first SBP measurement recorded as part of routine care after the study ended. Among patients who had controlled SBP at the final study visit, the proportions who had uncontrolled SBP during follow-up were compared for the intervention and usual care (UC) groups. Kaplan-Meier estimates assessed time to uncontrolled SBP by treatment arm.
Results:
Of 283 patients completing the Improving Blood Pressure in Colorado study, 51.5% in the intervention and 46.9% in the UC group had controlled SBP at the final study visit. Of patients with controlled SBP, 37.0% and 46.4% of patients in the intervention and UC groups, respectively, had uncontrolled SBP at their initial measurement during follow-up (P = .32). There was no difference in median time to uncontrolled SBP (126 vs 114 days for the intervention and UC groups, respectively; P = .47).
Conclusions:
SBP control was not maintained in a significant proportion of patients in both groups following hypertension study participation. These findings suggest the need for interventions to focus on longer-term BP control in contrast to the short duration of most hypertension intervention trials.
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