Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introspection01:29

Introspection

Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
Flashbulb Memory01:16

Flashbulb Memory

A flashbulb memory is a highly vivid and detailed memory, often linked to events of significant emotional impact. These memories stand out in contrast to everyday memories due to their clarity and the precision with which they are recalled. The strong emotions associated with the event act as a catalyst, ensuring that specific details, such as one's location, actions, and even peripheral elements, are etched into memory with remarkable accuracy. For example, many people can vividly recall where...
Sources of Self-Esteem I: Family Experience01:18

Sources of Self-Esteem I: Family Experience

Self-esteem, a crucial component of psychological development, is significantly shaped by familial experiences. The early parent-child relationship serves as a foundational influence on a child's self-concept, with long-lasting effects extending into adolescence and adulthood.Parental Behaviors and Early Self-Esteem FormationEmpirical studies have identified four principal parental behaviors that foster healthy self-esteem in children. These include expressions of acceptance, affection, and...
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
Sources of Self-Esteem II: Performance Feedback01:24

Sources of Self-Esteem II: Performance Feedback

Self-esteem is intricately tied to our perception of competence and our ability to exert control over our lives. One of the primary sources of this perception is performance feedback — the ongoing evaluation of our actions in terms of success and failure. According to Franks and Marolla (1976), people derive self-worth from experiencing themselves as causal agents, capable of achieving goals and overcoming obstacles. This process nurtures a critical component of self-esteem: self-efficacy,...
Framing Effects03:26

Framing Effects

Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in different ways based on the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins.

The Journal of biological chemistry·2006
Same author

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.

Proceedings of the National Academy of Sciences of the United States of America·2005
Same author

Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.

Proceedings of the National Academy of Sciences of the United States of America·2005
Same author

Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits.

Methods in enzymology·2004
Same author

Allosteric determinants in guanine nucleotide-binding proteins.

Proceedings of the National Academy of Sciences of the United States of America·2003
Same author

TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.

The Journal of biological chemistry·2003

Related Experiment Video

Updated: May 30, 2026

Use of Autometallography to Localize and Semi-Quantify Silver in Cetacean Tissues
07:05

Use of Autometallography to Localize and Semi-Quantify Silver in Cetacean Tissues

Published on: October 4, 2018

Silver spoons and other personal reflections.

Alfred G Gilman1

  • 1The Cancer Prevention and Research Institute of Texas, Dallas, Texas 75390, USA. agilman@cprit.state.tx.us

Annual Review of Pharmacology and Toxicology
|August 9, 2011
PubMed
Summary
This summary is machine-generated.

This narrative explores a 50-year journey in biomedical science, detailing personal experiences and scientific evolution. It offers insights into the dynamic field of life sciences research.

More Related Videos

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting
08:32

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting

Published on: May 14, 2016

Related Experiment Videos

Last Updated: May 30, 2026

Use of Autometallography to Localize and Semi-Quantify Silver in Cetacean Tissues
07:05

Use of Autometallography to Localize and Semi-Quantify Silver in Cetacean Tissues

Published on: October 4, 2018

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting
08:32

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting

Published on: May 14, 2016

Area of Science:

  • Biomedical Science: Encompassing a broad spectrum of life sciences research and development.
  • Medical Research: Detailing advancements and personal contributions over five decades.

Background:

  • Personal narrative spanning 50 years of a career in biomedical science.
  • Chronicles the period from 1961 to the present, highlighting key life stages and professional milestones.

Discussion:

  • Reflects on the transformative impact of scientific discoveries and technological innovations.
  • Examines the personal and professional challenges and triumphs within the biomedical field.

Key Insights:

  • The evolution of biomedical research methodologies and their implications.
  • The interplay between personal dedication and scientific progress in a long-term career.
  • Anecdotal evidence of the scientific community's growth and adaptation.

Outlook:

  • Future perspectives on biomedical science based on historical trends and personal experience.
  • The enduring importance of curiosity and perseverance in scientific exploration.