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Related Concept Videos

Longitudinal Research02:20

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Longitudinal Studies01:26

Longitudinal Studies

Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...

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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Stillbirth Collaborative Research Network: design, methods and recruitment experience.

Corette B Parker1, Carol J R Hogue, Matthew A Koch

  • 1RTI International, Research Triangle Park, NC 27709-2194, USA. rette@rti.org

Paediatric and Perinatal Epidemiology
|August 9, 2011
PubMed
Summary

The Stillbirth Collaborative Research Network (SCRN) conducted a large case-control study on stillbirths and livebirths. This research aims to identify risk factors and understand the scope of stillbirths.

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Area of Science:

  • Obstetrics and Gynecology
  • Perinatal Epidemiology
  • Public Health Research

Background:

  • Stillbirth remains a significant public health concern with complex etiologies.
  • Previous research has been limited by sample size and scope.
  • Understanding risk factors is crucial for prevention strategies.

Purpose of the Study:

  • To describe the design, methods, and recruitment experience of the Stillbirth Collaborative Research Network (SCRN) study.
  • To establish a population-based cohort for investigating stillbirth causes and risk factors.
  • To assess the incidence and scope of stillbirth within defined geographical areas.

Main Methods:

  • A multisite, population-based, case-control study with prospective enrollment of stillbirths and livebirths.
  • Standardized data collection including maternal interviews, medical record abstraction, placental pathology, and biospecimen testing.
  • Oversampling of livebirths <32 weeks gestation and women of African descent to ensure representation.

Main Results:

  • The SCRN enrolled 663 women with stillbirths and 1932 women with livebirths between March 2006 and September 2008.
  • High consent rates were achieved for maternal interviews (95% for stillbirths), chart abstraction (95% for stillbirths), placental pathology (95% for stillbirths), and fetal post-mortem examinations (84% for stillbirths).
  • The study successfully recruited participants from 59 hospitals across five clinical sites, covering at least 90% of births in the catchment areas.

Conclusions:

  • The SCRN study design and recruitment methods were effective in establishing a comprehensive dataset for stillbirth research.
  • The high participation rates indicate feasibility for large-scale stillbirth investigations.
  • This study provides a robust foundation for systematically identifying causes and risk factors for stillbirth.