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Updated: May 30, 2026

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Documented intraoperative hypotension according to the three most common definitions does not match the application
M Franck1, F M Radtke, C Prahs
1Department of Anaesthesiology and Surgical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Insights
Anesthetists
Area of Science:
- Anesthesiology
- Critical Care Medicine
Background:
- Intraoperative hypotension (IOH) is a common concern during anesthesia.
- Existing definitions of IOH vary, impacting clinical decision-making.
- The relationship between IOH definitions and antihypotensive medication (AHM) administration requires clarification.
Purpose of the Study:
- To evaluate the association between common IOH definitions and anesthetists' AHM use.
- To compare the predictive accuracy of existing IOH definitions for AHM administration.
- To identify factors influencing anesthetists' decisions regarding IOH management.
Main Methods:
- Observational study of 2350 patients undergoing mixed surgical procedures.
- Analysis of three standard definitions of IOH based on systolic blood pressure (SBP) thresholds and percentage fall.
- Comparison of prediction accuracy for AHM use and multivariate logistic analysis of associated factors.
Main Results:
- Existing IOH definitions showed moderate accuracy (54-67%) in predicting AHM use.
- A novel definition (SBP < 92 mmHg or > 24% fall) demonstrated slightly improved prediction (68%).
- IOH, by any definition, was not significantly associated with postoperative inpatient stay.
Conclusions:
- Current IOH definitions have limited correlation with anesthetists' clinical judgment for AHM administration.
- Anesthetists consider multiple perioperative factors beyond SBP when managing IOH.
- Patient age, physical status, and surgical characteristics better predict postoperative stay than IOH itself.
Abstract:
This observational study investigated which of the three most common definitions of intraoperative hypotension (IOH), reported in a published systematic literature review, were associated best with anaesthetists' administration of antihypo tensive medication (AHM). IOH and AHM use in anaesthetic procedures in a mixed surgical population (n = 2350) were also reviewed. The definitions were: arterial systolic blood pressure (SBP) < 100 mmHg or a fall in SBP of > 30% of the preoperative SBP baseline; arterial SBP < 80 mmHg; a fall in SBP of > 20% of the preoperative SBP. Accuracy of predicting AHM using these three definitions was 67%, 54% and 65%, respectively. Prediction by a new fourth definition, using an optimal threshold of minimal SBP falling to < 92 mmHg or by > 24% of preoperative baseline, was 68% accurate. In multivariate logistic analysis, age, volatile versus intravenous anaesthetics, medical history of arterial hypertension and all four definitions of IOH were associated with intraoperative AHM, however IOH was not associated with postoperative in-patient stay. The three original definitions correlated poorly with the anaesthetist's judgement about applying AHM. Anaesthetists make complex decisions regarding the relevance of IOH, considering various perioperative factors in addition to SBP. Age, physical status and duration and type of surgery showed better correlations with postoperative in-patient stay than IOH.
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