Documented intraoperative hypotension according to the three most common definitions does not match the application

M Franck1, F M Radtke, C Prahs

  • 1Department of Anaesthesiology and Surgical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Insights

Anesthetists

Area of Science:

  • Anesthesiology
  • Critical Care Medicine

Background:

  • Intraoperative hypotension (IOH) is a common concern during anesthesia.
  • Existing definitions of IOH vary, impacting clinical decision-making.
  • The relationship between IOH definitions and antihypotensive medication (AHM) administration requires clarification.

Purpose of the Study:

  • To evaluate the association between common IOH definitions and anesthetists' AHM use.
  • To compare the predictive accuracy of existing IOH definitions for AHM administration.
  • To identify factors influencing anesthetists' decisions regarding IOH management.

Main Methods:

  • Observational study of 2350 patients undergoing mixed surgical procedures.
  • Analysis of three standard definitions of IOH based on systolic blood pressure (SBP) thresholds and percentage fall.
  • Comparison of prediction accuracy for AHM use and multivariate logistic analysis of associated factors.

Main Results:

  • Existing IOH definitions showed moderate accuracy (54-67%) in predicting AHM use.
  • A novel definition (SBP < 92 mmHg or > 24% fall) demonstrated slightly improved prediction (68%).
  • IOH, by any definition, was not significantly associated with postoperative inpatient stay.

Conclusions:

  • Current IOH definitions have limited correlation with anesthetists' clinical judgment for AHM administration.
  • Anesthetists consider multiple perioperative factors beyond SBP when managing IOH.
  • Patient age, physical status, and surgical characteristics better predict postoperative stay than IOH itself.

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