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Published on: October 2, 2020

Lipids, waist circumference and body mass index in haemodialysis patients

S Bevc1, A Potočnik, R Hojs

  • 1Department of Dialysis, Clinic for Internal Medicine, University Medical Centre Maribor, Maribor, Slovenia. sebastjanb@yahoo.com

The Journal of International Medical Research
|August 9, 2011
PubMed

Insights

Abdominal obesity and body mass index (BMI) are linked to altered blood lipid profiles in patients undergoing maintenance haemodialysis (HD). Specifically, higher triglycerides were seen in obese men, while women showed reduced HDL cholesterol with increased abdominal obesity.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Metabolic Disorders

Background:

  • Dyslipidemia and abdominal obesity are established cardiovascular disease risk factors in the general population.
  • Their specific roles in patients undergoing maintenance haemodialysis (HD) remain less understood.
  • Understanding these associations is crucial for managing cardiovascular risk in this vulnerable group.

Purpose of the Study:

  • To investigate the association between blood lipid profiles and measures of abdominal obesity (waist circumference, WAC) and body mass index (BMI) in maintenance HD patients.
  • To explore potential sex-specific differences in these associations.
  • To identify key metabolic risk factors contributing to cardiovascular disease in HD patients.

Main Methods:

  • Cross-sectional study involving 72 maintenance HD patients (32 women).
  • Measurements included blood lipid levels (triglycerides, HDL cholesterol, apolipoprotein A), waist circumference (WAC), and body mass index (BMI).
  • Statistical analysis was performed to determine correlations between obesity measures and lipid parameters, with stratification by sex.

Main Results:

  • Abdominal obesity (WAC) was prevalent in 62.5% of HD patients (75% of women, 52.5% of men).
  • Abdominally obese men had higher triglyceride levels compared to non-obese men.
  • In men, WAC and BMI positively correlated with triglyceride levels. In women, WAC negatively correlated with HDL cholesterol and apolipoprotein A levels.
  • A significant negative association was observed between abdominal obesity/BMI and HDL cholesterol in the overall HD patient cohort.

Conclusions:

  • Abdominal obesity is common in maintenance HD patients and is associated with dyslipidemia.
  • The relationship between obesity, BMI, and lipid profiles, particularly HDL cholesterol, differs between men and women on HD.
  • These findings highlight the importance of assessing abdominal obesity and BMI for cardiovascular risk stratification in HD patients.

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